Advanced Training        Post-Graduation; E-Learning; Ph.D. Thesis(Completed and On-going); Completed Euro-Masters

Post-Graduation Courses

3. "Structure and Conformation of Carbohydrates. NMR and Molecular Recognition", lectured by Jesus Jiménez Barbero, Filipa Marcelo and Ana Arda (Centro de Investigaciones Biológicas, CSIC, Spain, in 2011

2. "Industrial Drug Research" lectured by Dr. Hans Peter Wessel, Hoffmann-La Roche, Basel, Switzerland, 2010

1. "Molecular Mechanisms of Drugs" lectured by Prof. Beat Ernst, Universidade de Basel, Switzerland, in 2009

E-Learning Course

Glycobiology & Glycochemistry e-learning course, starting in 2014

Completed Ph. D.s

1. "The first synthesis of glycosylflavanones catalysed by praseodymium triflate: a straightforward approach to potential antidiabetic agents", Rui Miguel Galhano dos Santos Lopes, SFRH/BD/30699/2006, supervised by Prof. Amélia Pilar Rauter (DQB-FCUL) and co-supervised by Prof. Jorge Justino (Instituto Politecnico de Santarem/Escola Superior Agraria) Universidade de Lisboa, 2013.

2. "Study of the bioactive extracts of Salvia sclareoides Brot. and Asteriscus vogelii (Webb.) Walp. and research on their bioactive principles", Isabel Maria Martins Horta Branco, supervised by Prof. Amélia Pilar Rauter (DQB-FCUL), Universidade de Lisboa, 2011.

3. "Synthesis of new sugar derivatives containing an α,β-unsaturated carbonyl system in their structure and biological evaluation" Nuno Manuel Ribeiro Martins Xavier, SFRH/BD/39251/2007, supervised by Prof. Amélia Pilar Rauter (DQB-FCUL) and co-supervised by Dr. Yves Queneau (Université de Lyon, France), Universidade de Lisboa, 2011.

4. "Polyfunctionalized carbohydrate-derived scaffolds for the production of libraries of bioactive compounds", Ana Catarina de Araújo Silva, SFRH/BD/17815/2004, supervised by Prof. Amélia Pilar Rauter (DQB-FCUL) and co-supervised by Prof. Francesco Nicotra (Università degli Studi di Milano-Bicocca, Italy), Universidade de Lisboa, 2010, European Ph.D..

5. "Selective Anchoring of Cyclic Thionocarbamates on Ketohexoses", Ana Catarina Simão, SFRH/BD/25891/2005, supervised by Prof. Amélia Pilar Rauter (DQB-FCUL), co-supervised by Prof. Patrick Rollin (Université d'Orléans, France) and Prof. Jorge Justino (Instituto Politecnico de Santarem/Escola Superior Agraria), Université d’Orléans, 2009.

6. "Carbohydrate-based 1,3-oxazoline-2-thiones as original bioactive structures. Synthesis and reactivity", Sandrina Isabel Ribeiro Martins da Silva, SFRH/BD/16937/2004, supervised by Prof. Amélia Pilar Rauter (DQB-FCUL), co-supervised by Prof. Jorge Justino (Instituto Politecnico de Santarem/Escola Superior Agraria) and Prof. Patrick Rollin (Université d'Orléans, France), Universidade de Lisboa, 2009.

7. "Total Synthesis and Stereochemical Assignment of Miharamycins", Filipa Margarida Barradas de Morais Marcelo, SFRH/BD/17775/2004, supervised by Prof. Amélia Pilar Rauter (DQB-FCUL), co-supervised by Prof. Jorge Justino (Instituto Politecnico de Santarem/Escola Superior Agraria) and Prof. Pierre Sinaÿ (Universite Pierre et Marie Curie, Paris, France), Universidade de Lisboa, 2009.

8. "Synthesis of gem-difluorocarbasugars", João Carlos Falcão Sardinha, SFRH/BD/17839/2004, co-supervisão de Prof. Pierre Sinaÿ (Universite Pierre et Marie Curie, Paris, France), Universidade de Lisboa, 2009.

9. "Oxetane delta-Amino Acids: Synthesis and Derivatization", Susana Dias Lucas, SFRH/BD/16592/2004, co-supervised by Dr. Hans Peter Wessel (Hoffmann-La Roche, Switzerland), Universidade de Lisboa, 2009.

10. "Synthetic approaches for the condensation of sugars with O-, N- and S-nucleophiles", Tânia Vanessa Santos de Almeida, SFRH/BD/3306/2000, Universidade de Lisboa, 2006.

11. "Contribution to the phytochemical study of plants endemic to Madeira Island: Flavonoids and 10lkaloids from Genista tenera", Alice Martins, co-supervised by Prof. Jorge Justino (Instituto Politécnico de Santarém) and Prof. Carlos Borges (DQB-FCUL), Universidade de Lisboa, 2006.

12. "Nitrenium ion chemistry: Investigation of the intramolecular cyclization of ethyl omega-(azidophenil)-2-phenylalcanoates", Orlando da Silva Pinto, Universidade de Lisboa, 2003.

13. "Synthesis of sugars containing butenolides in their structure", Tana Lukeba Canda, Universidade de Lisboa, 2002.

Supervision of not yet completed Ph.D. grants

Eight Ph.D. students are currently developing their research projects, two of them in the company CIPAN and one of them is a co-supervision within a collaboration established with the Universidade do Algarve.

The Ph.Ds that are currently supervised and co-supervised are listed below:

1. Ana Marta de Jesus Gomes de Matos, From a multitarget antidiabetic glycosyl isoflavone towards new molecular entities against diabetes and Alzheimer’s disease: generation of lead series and target assessment, SFRH/BD/93170/2013, supervised by Prof. Amélia Pilar Rauter, co-supervised by Prof. Paula de Macedo (Faculdade de Ciências Médicas, Universidade de Lisboa).

2. Vasco Miguel Candeias Cachatra, New synthetic strategies and structural optimization of the sugar moiety from a selective butyrylcholinesterase inhibitor, SFRH/BD/90359/2012, supervised by Prof. Amélia Pilar Rauter.

3. Catarina Alexandra dos Santos Dias, New Molecular Entities for multitarget therapeutics: infeccious and neurodegenerative diseases,, SFRH/BDE/51998/2012, Ph. D. in company (CIPAN) supervised by Prof. Amélia Pilar Rauter and co-supervised by Dr. Dália Barbosa (CIPAN).

4. João Pedro de Almeida Pais, Development of new anibiotics efficient against Bacillus anthracis, SFRH/BDE/51957/2012, Ph. D. in company (CIPAN)supervised by Prof. Amélia Pilar Rauter and co-supervised by Dr. Dália Barbosa (CIPAN) and by Dr. Ricardo Dias (BIOFIG, FCUL).

5. Ana Rita Xavier de Jesus, Chemoenzymatic Synthesis of Sodium-Glucose Co-Transporters Sugar-Based Inhibitors for the Treatment of Diabetes, SFRH/BD/78236/2011, supervised by Prof. Amélia Pilar Rauter and co-supervised by Prof. Jian Liu (School of Pharmacy, The University of North Carolina at Chaper Hill), and by Prof. Timothy Dore (New York University ABU DHABI).

6. Catarina Vizetto Guerreiro Duarte, Antitumoural activity of Cystoseira species: insights into the mechanism of action, SFRH/BD/81425/2011, supervised by Prof. João Varela (Universidade do Algarve) and co-supervised by Prof. Fernando Alberício (IRB, Barcelona, Spain and Universidad Yachay, Equador) and Prof. Amélia Pilar Rauter.

7. Lina Paula Bento Falcão, História, materiais e técnicas dos cabedais decorativos e artísticos europeus produzidos entre 1500 e 1800, SFRH/BD/62704/2009, supervised by Prof. M. Eduarda Araújo and co-supervised by Prof. Fernando António Baptista Pereira (coordinator of Centro de Investigação e de Estudos em Belas Artes: Instituto Francisco de Holanda and Professor at Faculdade de Belas-Artes da Universidade de Lisboa).

8. Lara Sofia Marques Ribeiro, N-nitrosoguanidinas difuncionais e reacções de transnitrosação, SFRH/BD/64404/2009, supervised by Prof. M. Eduarda Araújo and co-supervised by Prof. Luis Garcia Rio, (Departamiento de Quimica-Fisica Facultad de Química de la Universidad de Santiago de Compostela).

Participation in FCT- PhD thematic programs:

Doctoral Program in Environmental Health from the Faculty of Medicine, University of Lisbon - "EnviHealth&Co", approved by FCT 2014 - N. M. Xavier (Sponsor of CQB).

Doctoral Program in Catalysis and Sustainability from Instituto Superior Técnico - "CATSUS", approved by FCT 2013 - A. P. Rauter, M. E. Araujo (Participants from FCUL).

Completed Masters

1. "Bioactivity of the Aloe arbadensis Miller syrup – an old recipe of the Franciscans Fryers", Liliana Marília Lage da Silva, Euromaster in Chemistry (Chemistry, Health and Nutrition), supervised by M Eduarda M Araújo, 2013.

2. "Química exploratória para o desenvolvimento de novos agentes antimicrobianos a partir de açúcares", Vasco Cachatra, Euromaster in Chemistry (Chemistry, Health and Nutrition), supervised by Prof. Amélia Pilar Rauter (DQB-FCUL), co-supervisão de Dr. Dália Dias Barbosa (CIPAN), Faculdade de Ciências da Universidade de Lisboa, 2012 .

3. "Síntese de derivados da xilose com potencial aplicação como agentes antimicrobianos", Patrícia Serra, Euromaster in Chemistry (Chemistry, Health and Nutrition), supervised by Prof. Amélia Pilar Rauter (DQB-FCUL), co-supervisão de Dr. Dália Dias Barbosa (CIPAN), Faculdade de Ciências da Universidade de Lisboa, 2012 .

4. "Searching for potential antibiotic agents of natural and synthetic origin and their interaction with amyloid fibril formation systems", Catarina Alexandra dos Santos Dias, Euromaster in Chemistry (Chemistry, Health and Nutrition), co-supervisão de Dr. Dália Dias Barbosa (CIPAN), Faculdade de Ciências da Universidade de Lisboa, 2012.

5. "Síntese de um potencial inibidor daβ-secretase e sua interação com o enzima", Rita Pereira, Master in Biochemistry, co-supervised by Prof. Amélia Pilar Rauter (DQB-FCUL) and supervised by Isabel Ismael, Universidade da Beira Interior, 2012.

6. "Synthesis and biological study of deoxy glycosides with potential antimicrobial activity against Bacillus spp", João Pedro de Almeida Pais, Euromaster in Chemistry (Chemistry, Health and Nutrition), supervised by Prof. Amélia Pilar Rauter (DQB-FCUL), co-supervisão de Dr. Ricardo Dias (BIOFIG) and co-supervisão de Dr. Dália Dias Barbosa (CIPAN), Faculdade de Ciências da Universidade de Lisboa, 2011.

7. "Valorisation of medicinal plants in terms of their active principles" (Valorização de plantas medicinais em termos dos seus princípios activos), Diana Godinho Mendes, Euromaster in Chemistry (Chemistry, Health and Nutrition), co-supervisão de Dr. John McAdam (ERVITAL), Faculdade de Ciências da Universidade de Lisboa, 2011.

8. "Study of medicinal plants from Montemuro Mountains" (Estudo de plantas medicinais da Serra de Montemuro), Maria Pilar Ribeiro Dias, Euromaster in Chemistry (Chemistry, Health and Nutrition), co-supervisão de Dr. John McAdam (ERVITAL), Faculdade de Ciências da Universidade de Lisboa, 2011.

9. "Synthesis of antidiabetic agents derived from C-glycosyl flavonoids", Ana Rita Xavier de Jesus, Euromaster in Chemistry (Chemistry, Health and Nutrition), Faculdade de Ciências da Universidade de Lisboa, 2010.

10. "Bioactivity of honey: antioxidant and antimicrobial activities and the composition in organic acids", Marina Filipa Paixão Domingos Lopes, Master in Biochemistry, co-supervisor and supervision of Prof. Célia Silva (Universidade dos Açores), Faculdade de Ciências da Universidade de Lisboa, 2010.

11. "Study of the reaction of N-nitrosocompounds with amino-acids containing a thiol group", Lara Sofia Marques Ribeiro, Euromaster in Chemistry (Chemistry, Health and Nutrition), supervised by M Eduarda M Araújo, 2010.

12. "Characterization of tannins used in vegetal leather tanning of European leathers from the 17th -19th centuries", Lina Paula Bento Falcão, Master Thesis in Chemistry Applied to the Cultural Heritage, supervised by M Eduarda M Araújo 2009.

13. "Ionic liquids as solventes in the oxidation reaction of sterols by pyridinium chlorocromate (PCC)", André Leal Gameiro, Euromaster in Technological Chemistry, supervised by M Eduarda M Araújo, 2008.

14. "Synthesis of potential agrochemicals from sugars", João Miguel da Cruz Morgado Agostinho Caio, Euromaster in Chemistry (Chemistry, Health and Nutrition), Faculdade de Ciências da Universidade de Lisboa, 2008.

15. "Phenols glycosylation under heterogeneous catalysis promoted by acid zeolites", Miguel Maurício Machado dos Santos, co-supervision of Prof. Ana Paula Carvalho, Euromaster in Chemistry (Chemistry,Health and Nutrition), Faculdade de Ciências da Universidade de Lisboa, 2008.

16. "A new method for the synthesis of 2-C-alkenes from 3-keto sugars", Joana Neves Lemos Salta, Euromaster in Chemistry (Chemistry, Health and Nutrition), Faculdade de Ciências da Universidade de Lisboa, 2008.

17. "Characterization of polychromic materials and techniques of the Portuguese wood sculpture from the erudite and popular production of the Barroque era (Caracterização de Materiais e de Técnicas de Policromia da Escultura Portuguesa sobre madeira de Produção Erudita e de Produção popular da Época Barroca)", Carolina Sofia Sarrazola Barata, Master Thesis in Chemistry Applied to the Cultural Heritage, co-supervised by M Eduarda M Araújo with António João Cruz. J. Cruz, Instituto Politécnico de Tomar, 2008.

18. "Biodiesel Production from Ricinus communis L. oil", Cleia da Guia Lages do Nascimento, Euromaster in Technological Chemistry, co-supervised by M Eduarda M Araújo with Ana Cristina Oliveira, DER, INETI, 2008

19. "Alterations on Paper of the Graphical Work of Rafael Bordalo Pinheiro", Aida Nunes, co-supervision of Prof. António João Cruz, Master in Chemistry Applied to the Cultural Heritage, Faculdade de Ciências da Universidade de Lisboa, 2006.

20. "Diterpenes from Plectranthus ornatus Codd. Carbamoil derivatives and antimicrobiane activity", Patrícia Dias de Mendonça Rijo, Master Thesis in Organic Pharmaceutical Chemistry, co-supervised by M Eduarda M Araújo with Fatima Simões Mestrado em Química Orgânica Farmacêutica, Faculdade de Farmácia da Universidade de Lisboa, 2003.

Post-Doc. Grants

1. "Síntese de polifenóis C-glicosilados com actividade antidiabética e de seus análogos: investigação de novas metodologias", Nuno M. Xavier, Junho – Agosto de 2012 (financiada pelo projecto "New antidiabetic agents from Genista tenera - Isolation, structure characterization, synthesis and mechanisms of action" (PTDC/QUI/67165/2006).

2. "Synthesis and lead optimization of nucleosides which are selective and potent inhibitors of butyrylcholinesterase", Stefan Schwarz (bolsa FCT, 2012-2013).

3. "Screening for Biological Activities from Marine Photosynthetic Organisms from the Algarve Coast", Luísa Margarida Batista Custódio, co-supervisão com João Carlos Serafim Varela, Centro de Ciências do Mar and Alberício Palomera, Barcelona Science Park (bolsa FCT, 2010-2013)

4. "Added-value polyphenols from vegetable biomass residues: perspective for reduction of the environment pollution", Maria Luísa de Bivar Weinholtz Roseiro (bolsa FCT, 2009-2012)

5. "Synthesis of alkyl deoxy glycosides and bioactivity studies", Alice Isabel Mendes Martins (bolsa FCT, 2008-2012 com renovação solicitada).

6. "Study of agronomic production of Salvia species and evaluation of their components for the potential control of the Alzheimer disease", Maria Filipa Vinagre Marques da Silva, co-supervisão de Prof. Jorge Justino, Instituto Politécnico de Santarém, bolsa do projecto PTDC/AGR-AAM/66414/2006 (2006-2007).

7. "Studies on the toxicity of the bioactive compounds derived from sugars", Margarida Goulart de Medeiros, co-supervisão de Prof. Jorge Justino, Instituto Politécnico de Santarém (bolsa FCT, 2004-2007).

8. "Synthesis of structural units and analogues of miharamycins. Study of their antibiotic and fungicidal activities", Maria Filipa Vinagre Marques da Silva, co-supervised by Prof. Jorge Justino, Instituto Politécnico de Santarém (bolsa FCT, 2003-2006).

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